Progressive Care Nursing Certification (PCCN) Practice Exam

What is the main purpose of monitoring serum creatinine in patients taking cyclosporine?

1. To assess for liver function

2. To check for renal injury

3. To evaluate electrolyte balance

4. To monitor blood glucose levels

The correct answer is: To check for renal injury

Monitoring serum creatinine in patients taking cyclosporine primarily serves to check for renal injury. Cyclosporine is an immunosuppressant commonly used in transplant patients and those with autoimmune disorders, but it can be nephrotoxic. Elevated levels of serum creatinine are indicative of impaired kidney function, signaling potential damage or stress to the kidneys. By routinely measuring serum creatinine levels in patients on cyclosporine therapy, healthcare providers can detect renal impairment early and make necessary adjustments to the medication dosage, hydration status, or overall treatment plan. This proactive approach helps in minimizing the risk of serious renal complications associated with cyclosporine use. In contrast, while monitoring may involve assessing liver function or electrolyte balance in other contexts, these are not the primary concerns directly related to cyclosporine therapy. Similarly, monitoring blood glucose levels is relevant in certain treatments, particularly those involving steroids or certain diabetes conditions, but it is not a direct concern when administering cyclosporine. The emphasis on serum creatinine specifically highlights its role as a key marker for renal function in this patient population.